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Expression of recombinant human butyrylcholinesterase in the milk of transgenic mice
Dan LU,Shengzhe SHANG,Shen LIU,Ying WU,Fangfang WU,Tan TAN,Qiuyan LI,Yunping DAI,Xiaoxiang HU,Yaofeng ZHAO,Ning LI
Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 3, Pages 179-184 doi: 10.15302/J-FASE-2014020
Keywords: recombinant human butyrylcholinesterase (rhBCHE) human lactoferrin bacterial artificial chromosome (hLF
High-expression of recombinant human concensus interferon-α by Pichia pastoris
HAO Yuyou, SHI Qiqi, HE Yun, ZHUANG Yingping, WANG Yonghong, ZHANG Siliang, CHU Ju, LIU Zhimin
Frontiers of Chemical Science and Engineering 2007, Volume 1, Issue 4, Pages 399-403 doi: 10.1007/s11705-007-0073-x
Keywords: bioactivity pastoris maximum induction optimized
Shen LIU, Shengzhe SHANG, Xuezhen YANG, Huihua ZHANG, Dan LU, Ning LI
Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 3, Pages 382-389 doi: 10.15302/J-FASE-2018211
The mammary gland provides a novel method for producing recombinant proteins in milk of transgenic>) was modified twice by homologous recombination to produce a universal expression vector, and the humanpronuclei of fertilized mouse embryos, to successfully generate two transgenic mouse lines that expressed recombinanthuman lysozyme (rhLZ) in milk.
Keywords: BAC recombinant methods gene expression human lysozyme transgenic mice milk expression vector
Ling HOU, Xiaoping LUO, Minlian DU, Huamei MA, Chunxiu GONG, Yuchuan LI, Shuixian SHEN, Zhuhui ZHAO, Li LIANG, Guanping DONG, Chaoying YAN, Hongwei DU
Frontiers of Medicine 2009, Volume 3, Issue 2, Pages 171-176 doi: 10.1007/s11684-009-0027-4
Keywords: recombinant human growth hormone injection growth hormone deficiency
Wei Wang, Shuqin Jiang, Zhirui Cui, Xiangyang Luo, Lingli Shi, Heli Zheng
Frontiers of Medicine 2018, Volume 12, Issue 5, Pages 580-585 doi: 10.1007/s11684-017-0585-9
Keywords: therapeutic idiopathic short-stature children free T4 the first year recombinant human growth hormone
FAN Xiaodong, HAN Ruifa
Frontiers of Medicine 2007, Volume 1, Issue 4, Pages 377-380 doi: 10.1007/s11684-007-0073-8
Keywords: Urology powerful 2b-BCG Tianjin institute wild-type
Expression and function of DMT1 without IRE in C6 cells mediated by recombinant adenovirus
Xixun DU*, Huamin XU*, Hong JIANG, Jun WANG, Lei WANG, Junxia XIE
Frontiers of Medicine 2009, Volume 3, Issue 1, Pages 67-71 doi: 10.1007/s11684-009-0010-0
Keywords: divalent metal transporter 1 recombinant adenovirus homologous recombination iron
Frontiers of Medicine 2022, Volume 16, Issue 6, Pages 919-931 doi: 10.1007/s11684-021-0918-6
Keywords: preeclampsia recombinant protein diannexin microparticle NLRP3 inflammasome phosphatidylserin
High-level expression of recombinant IgG1 by CHO K1 platform
Ningning Xu, Jianfa Ou, Al-Karim (Al) Gilani, Lufang Zhou, Margaret Liu
Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 3, Pages 376-380 doi: 10.1007/s11705-015-1531-5
Keywords: Chinese hamster ovary (CHO) monoclonal antibody IgG1 amplification cell line development
Regulation of exogenous bFGF gene mediated by recombinant adeno-associated virus
Ke SONG, Nianjing RAO, Meiling CHEN, Yingguang CAO
Frontiers of Medicine 2009, Volume 3, Issue 2, Pages 158-163 doi: 10.1007/s11684-009-0042-5
Keywords: tetracycline regulatory system adeno-associated virus basic fibroblast growth factor gene regulation
Regulatory issues for genetically modified animals
Perry Bradbury HACKETT
Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 188-203 doi: 10.15302/J-FASE-2019307
Precision genetics and breeding have the potential to meet the agricultural needs and goals of the world in the 21st century. These needs include increasing the efficiency of production of animals and improving their products with minimal impact on the environment. The USA is the major innovator in genomic science and the acknowledged leader in formulating policies to regulate genetic applications in medicine and agriculture. However, governments worldwide have been exceedingly reluctant to support the introduction of genetically modified (GM) animals into agriculture. Regulatory policies have stagnated due to legal guidelines that could not anticipate the needs and solutions that are evident today. This must change if we are to maintain planetary integrity. I propose a new, market-based regulatory model for GM livestock that has both a strong scientific foundation and has worked for 10000 years. The model is similar to that for information technology in which specific algorithms drive computer and cell phone applications. Genome engineers write genetic algorithms that drive the traits in biological organisms. Accordingly, GM products should be viewed in terms of their use and public benefit rather than by limitations to the genetic programing coming from a few highly vocal groups. Genetic algorithms (Genapps) of the 21st century will include not only introduction of synthetic genes, but also complete natural and synthetic biochemical pathways to produce agricultural products that are maximally efficient, healthy to humans and animals, and sustainable in an era of changing climates while avoiding environmental degradation.
Keywords: algorithms editing FDA GMO recombinant DNA USDA
Challenges of human–machine collaboration in risky decision-making
Frontiers of Engineering Management 2022, Volume 9, Issue 1, Pages 89-103 doi: 10.1007/s42524-021-0182-0
Keywords: human–machine collaboration risky decision-making human–machine team and interaction task allocation human–machine relationship
T. G. YUDINA, Danyang GUO, N. F. PISKUNKOVA, I. B. PAVLOVA, L. L. ZAVALOVA, I. P. BASKOVA
Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 2, Pages 203-209 doi: 10.1007/s11705-012-1277-2
Keywords: recombinant destabilase-lysozyme (rec.Dest-Lys) antimicrobial activity antifungal activity medicinal
Zooming in and out of ferroptosis in human disease
Frontiers of Medicine 2023, Volume 17, Issue 2, Pages 173-206 doi: 10.1007/s11684-023-0992-z
Keywords: ferroptosis human disease iron metabolism lipid peroxidation antioxidation
Dan DAI, Jing LIU
Frontiers in Energy 2012, Volume 6, Issue 3, Pages 210-226 doi: 10.1007/s11708-012-0200-3
Keywords: human energy harvesting human-powered transportation human-powered home appliances human-powered grid(HPG) human-powered charger (HPC) human-powered storage (HPS) biofuel
Title Author Date Type Operation
Expression of recombinant human butyrylcholinesterase in the milk of transgenic mice
Dan LU,Shengzhe SHANG,Shen LIU,Ying WU,Fangfang WU,Tan TAN,Qiuyan LI,Yunping DAI,Xiaoxiang HU,Yaofeng ZHAO,Ning LI
Journal Article
High-expression of recombinant human concensus interferon-α by Pichia pastoris
HAO Yuyou, SHI Qiqi, HE Yun, ZHUANG Yingping, WANG Yonghong, ZHANG Siliang, CHU Ju, LIU Zhimin
Journal Article
Construction of a universal recombinant expression vector that regulates the expression of human lysozyme
Shen LIU, Shengzhe SHANG, Xuezhen YANG, Huihua ZHANG, Dan LU, Ning LI
Journal Article
Clinical evaluation of recombinant human growth hormone injection in children with growth hormone deficiency
Ling HOU, Xiaoping LUO, Minlian DU, Huamei MA, Chunxiu GONG, Yuchuan LI, Shuixian SHEN, Zhuhui ZHAO, Li LIANG, Guanping DONG, Chaoying YAN, Hongwei DU
Journal Article
supplementation of thyroid hormone on treatment of idiopathic short-stature children during therapy with recombinanthuman growth hormone
Wei Wang, Shuqin Jiang, Zhirui Cui, Xiangyang Luo, Lingli Shi, Heli Zheng
Journal Article
Study of recombinant human IFN-α-2b bacilli Calmette–Guerin activated killer cells and against bladder
FAN Xiaodong, HAN Ruifa
Journal Article
Expression and function of DMT1 without IRE in C6 cells mediated by recombinant adenovirus
Xixun DU*, Huamin XU*, Hong JIANG, Jun WANG, Lei WANG, Junxia XIE
Journal Article
Recombinant protein diannexin prevents preeclampsia-like symptoms in a pregnant mouse model via reducing
Journal Article
High-level expression of recombinant IgG1 by CHO K1 platform
Ningning Xu, Jianfa Ou, Al-Karim (Al) Gilani, Lufang Zhou, Margaret Liu
Journal Article
Regulation of exogenous bFGF gene mediated by recombinant adeno-associated virus
Ke SONG, Nianjing RAO, Meiling CHEN, Yingguang CAO
Journal Article
Antifungal and antibacterial functions of medicinal leech recombinant destabilase-lysozyme and its heated-up
T. G. YUDINA, Danyang GUO, N. F. PISKUNKOVA, I. B. PAVLOVA, L. L. ZAVALOVA, I. P. BASKOVA
Journal Article